Yellow fever or black vomiting is a viral infectious disease, transmitted by mosquitoes in tropical and subtropical regions of Africa and South America. Fever, nausea and pain resolve after a few days. In severe cases, it can lead to sometimes fatal liver damage, jaundice or a blood clotting disorder. According to WHO estimates, about 200,000 people develop yellow fever each year, with the disease being fatal in 15% of cases. 90% of the infections occur on the African continent.
Since there is no known therapy for yellow fever, the vaccination for yellow fever, developed by Max Theiler is all the more important. It is considered to be very safe and effective. The live vaccine strain 17D was isolated by Theiler from a deceased in Ghana in 1937 and has since been propagated in incubated chicken eggs. In rare cases, the vaccine causes flu-like symptoms.
According to the WHO, the vaccine may only be administered to small children after nine months. Adults over the age of 60 are at increased risk of serious side effects, which is why their constitution must first be checked. A risk-benefit analysis must also be carried out for pregnant women; yellow fever vaccination should not be given for thymus diseases.